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Sticky platelet syndrome : ウィキペディア英語版 | Sticky platelet syndrome Sticky platelet syndrome is a term used by some to describe a disorder of platelet function. It was first described by Mammen in 1983. It is inherited in an autosomal dominant pattern. It has not been associated with a specific gene, and it is not recognized as an entity in OMIM. Among researchers using the term, it has been described as a coagulation disorder that can present in conjunction with protein S deficiency and Factor V Leiden. It is not currently known if sticky platelet syndrome is a distinct condition, or if it represents part of the presentation of a more well characterized coagulation disorder. ==Diagnosis== SPS is diagnosed by demonstrating platelet hyperaggregability. In a lab test called aggregometry platelet stickyness is stimulated with epinephrine (EPI) and/or adenosine diphosphate (ADP).〔http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1C-47T2D4S-4&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=fa06922a824e24db83382664b8659e30〕 This test is not possible for patients being treated with acetylsalicylic acid until that substance has sufficiently cleared from their system.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Sticky platelet syndrome」の詳細全文を読む
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